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Interference with Glycosaminoglycan-Chemokine Interactions with a Probe to Alter Leukocyte Recruitment and Inflammation In Vivo

In vivo leukocyte recruitment is not fully understood and may result from interactions of chemokines with glycosaminoglycans/GAGs. We previously showed that chlorite-oxidized oxyamylose/COAM binds the neutrophil chemokine GCP-2/CXCL6. Here, mouse chemokine binding by COAM was studied systematically...

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Detalles Bibliográficos
Autores principales: Li, Sandra, Pettersson, Ulrika S., Hoorelbeke, Bart, Kolaczkowska, Elzbieta, Schelfhout, Katrien, Martens, Erik, Kubes, Paul, Van Damme, Jo, Phillipson, Mia, Opdenakker, Ghislain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122422/
https://www.ncbi.nlm.nih.gov/pubmed/25093679
http://dx.doi.org/10.1371/journal.pone.0104107