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Adenosine A(2A) Receptors Activation Facilitates Neuromuscular Transmission in the Pre-Symptomatic Phase of the SOD1(G93A) ALS Mice, but Not in the Symptomatic Phase
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease leading to motor neuron dysfunction resulting in impairment of neuromuscular transmission. A(2A) adenosine receptors have already been considered as a potential therapeutical target for ALS but their neuromodulatory role at the neuro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122437/ https://www.ncbi.nlm.nih.gov/pubmed/25093813 http://dx.doi.org/10.1371/journal.pone.0104081 |