Adenosine A(2A) Receptors Activation Facilitates Neuromuscular Transmission in the Pre-Symptomatic Phase of the SOD1(G93A) ALS Mice, but Not in the Symptomatic Phase

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease leading to motor neuron dysfunction resulting in impairment of neuromuscular transmission. A(2A) adenosine receptors have already been considered as a potential therapeutical target for ALS but their neuromodulatory role at the neuro...

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Detalles Bibliográficos
Autores principales: Nascimento, Filipe, Pousinha, Paula A., Correia, Alexandra M., Gomes, Rui, Sebastião, Ana M., Ribeiro, Joaquim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122437/
https://www.ncbi.nlm.nih.gov/pubmed/25093813
http://dx.doi.org/10.1371/journal.pone.0104081

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