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Dual Transgene Expression in Murine Cerebellar Purkinje Neurons by Viral Transduction In Vivo

Viral-vector mediated gene transfer to cerebellar Purkinje neurons in vivo is a promising avenue for gene therapy of cerebellar ataxias and for genetic manipulation in functional studies of animal models of cerebellar disease. Here, we report the results of experiments designed to identify efficient...

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Detalles Bibliográficos
Autores principales: Bosch, Marie K., Nerbonne, Jeanne M., Ornitz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122438/
https://www.ncbi.nlm.nih.gov/pubmed/25093726
http://dx.doi.org/10.1371/journal.pone.0104062