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A Novel ATM/TP53/p21-Mediated Checkpoint Only Activated by Chronic γ-Irradiation
Different levels or types of DNA damage activate distinct signaling pathways that elicit various cellular responses, including cell-cycle arrest, DNA repair, senescence, and apoptosis. Whereas a range of DNA-damage responses have been characterized, mechanisms underlying subsequent cell-fate decisio...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122452/ https://www.ncbi.nlm.nih.gov/pubmed/25093836 http://dx.doi.org/10.1371/journal.pone.0104279 |