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Self-assembled nanoparticles based on the c(RGDfk) peptide for the delivery of siRNA targeting the VEGFR2 gene for tumor therapy

The clinical application of small interfering RNA (siRNA) has been restricted by their poor intracellular uptake, low serum stability, and inability to target specific cells. During the last several decades, a great deal of effort has been devoted to exploring materials for siRNA delivery. In this s...

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Detalles Bibliográficos
Autores principales: Liu, Li, Liu, Xiaoxia, Xu, Qian, Wu, Ping, Zuo, Xialin, Zhang, Jingjing, Deng, Houliang, Wu, Zhuomin, Ji, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122582/
https://www.ncbi.nlm.nih.gov/pubmed/25114522
http://dx.doi.org/10.2147/IJN.S63717