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IgG in cervicovaginal mucus traps HSV and prevents vaginal Herpes infections

IgG is the predominant immunoglobulin in cervicovaginal mucus (CVM), yet how IgG in mucus can protect against infections is not fully understood. IgG diffuses rapidly through cervical mucus, slowed only slightly by transient adhesive interactions with mucins. We hypothesize this almost unhindered di...

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Detalles Bibliográficos
Autores principales: Wang, Ying-Ying, Kannan, Arthi, Nunn, Kenetta L., Murphy, Michael A., Subramani, Durai B., Moench, Thomas, Cone, Richard, Lai, Samuel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122653/
https://www.ncbi.nlm.nih.gov/pubmed/24496316
http://dx.doi.org/10.1038/mi.2013.120