An Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells

BACKGROUND: One in eight women will be affected by breast cancer in her lifetime. Approximately 75% of breast cancers express estrogen receptor alpha (ERα) and/or progesterone receptor and these receptors are markers for tumor dependence on estrogen. Anti-estrogenic drugs such as tamoxifen are commo...

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Detalles Bibliográficos
Autores principales: Jung, Jae Woo, Shim, Sun Young, Lee, Dong Kun, Kwiatkowski, Witek, Choe, Senyon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122783/
https://www.ncbi.nlm.nih.gov/pubmed/25070479
http://dx.doi.org/10.1186/1471-2407-14-549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122783/
https://www.ncbi.nlm.nih.gov/pubmed/25070479
http://dx.doi.org/10.1186/1471-2407-14-549

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