Promoting E2F1-mediated apoptosis in oestrogen receptor-α-negative breast cancer cells

BACKGROUND: Because oestrogen receptor α (ERα) regulates E2F1 expression to mediate tamoxifen resistance in ERα-positive breast cancer cells, we aimed to define the possible roles of ERα and E2F1 in promoting the resistance of ERα-negative breast cancer cells to 4-hydroxy-tamoxifen (4OHT). METHODS:...

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Detalles Bibliográficos
Autores principales: Montenegro, María F, Collado-González, María del Mar, Fernández-Pérez, María Piedad, Hammouda, Manel B, Tolordava, Lana, Gamkrelidze, Mariam, Rodríguez-López, José Neptuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122786/
https://www.ncbi.nlm.nih.gov/pubmed/25064027
http://dx.doi.org/10.1186/1471-2407-14-539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122786/
https://www.ncbi.nlm.nih.gov/pubmed/25064027
http://dx.doi.org/10.1186/1471-2407-14-539

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