Human TRPM8 and TRPA1 pain channels, including a gene variant with increased sensitivity to agonists (TRPA1 R797T), exhibit differential regulation by SRC-tyrosine kinase inhibitor

TRPM8 (transient receptor potential M8) and TRPA1 (transient receptor potential A1) are cold-temperature-sensitive nociceptors expressed in sensory neurons but their behaviour in neuronal cells is poorly understood. Therefore DNA expression constructs containing human TRPM8 or TRPA1 cDNAs were trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Kevin, Sadofsky, Laura R., Crow, Christopher, Morice, Alyn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122973/
https://www.ncbi.nlm.nih.gov/pubmed/24975826
http://dx.doi.org/10.1042/BSR20140061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122973/
https://www.ncbi.nlm.nih.gov/pubmed/24975826
http://dx.doi.org/10.1042/BSR20140061

Ejemplares similares