Post-transcriptional regulation of the human reduced folate carrier as a novel adaptive mechanism in response to folate excess or deficiency

The RFC (reduced folate carrier) is the principal mechanism by which folates and clinically used antifolates are delivered to mammalian cells. hRFC (human RFC) is subject to complex transcriptional controls and exists as homo-oligomer. To explore the post-transcriptional regulation of hRFC by exogen...

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Detalles Bibliográficos
Autores principales: Hou, Zhanjun, Orr, Steve, Matherly, Larry H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122975/
https://www.ncbi.nlm.nih.gov/pubmed/24949876
http://dx.doi.org/10.1042/BSR20140065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122975/
https://www.ncbi.nlm.nih.gov/pubmed/24949876
http://dx.doi.org/10.1042/BSR20140065

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