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Deacetylation of the tumor suppressor protein PML regulates hydrogen peroxide-induced cell death

The promyelocytic leukemia protein (PML) is a tumor suppressor that is expressed at a low level in various cancers. Although post-translational modifications including SUMOylation, phosphorylation, and ubiquitination have been found to regulate the stability or activity of PML, little is known about...

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Detalles Bibliográficos
Autores principales: Guan, D, Lim, J H, Peng, L, Liu, Y, Lam, M, Seto, E, Kao, H-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123062/
https://www.ncbi.nlm.nih.gov/pubmed/25032863
http://dx.doi.org/10.1038/cddis.2014.185