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Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype

TNF-related apoptosis inducing ligand (TRAIL), a member of the TNF superfamily released by microglia, appears to be involved in the induction of apoptosis following focal brain ischemia. Indeed, brain ischemia is associated with progressive enlargement of damaged areas and prominent inflammation. As...

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Detalles Bibliográficos
Autores principales: Cantarella, G, Pignataro, G, Di Benedetto, G, Anzilotti, S, Vinciguerra, A, Cuomo, O, Di Renzo, G F, Parenti, C, Annunziato, L, Bernardini, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123080/
https://www.ncbi.nlm.nih.gov/pubmed/25032854
http://dx.doi.org/10.1038/cddis.2014.286