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Renin–angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma

Glaucoma, one of the leading causes of irreversible blindness, is characterized by progressive degeneration of optic nerves and retinal ganglion cells (RGCs). In the mammalian retina, excitatory amino acid carrier 1 (EAAC1) is expressed in neural cells, including RGCs, and the loss of EAAC1 leads to...

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Detalles Bibliográficos
Autores principales: Semba, K, Namekata, K, Guo, X, Harada, C, Harada, T, Mitamura, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123089/
https://www.ncbi.nlm.nih.gov/pubmed/25032856
http://dx.doi.org/10.1038/cddis.2014.296