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Pharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetes

Type I diabetes (T1D) is an autoimmune disease in which an immune response to pancreatic β-cells results in their loss over time. Although the conventional view is that this loss is due to autoimmune destruction, we present evidence of an additional phenomenon in which autoimmunity promotes islet en...

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Detalles Bibliográficos
Autores principales: Piran, R, Lee, S-H, Li, C-R, Charbono, A, Bradley, L M, Levine, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123101/
https://www.ncbi.nlm.nih.gov/pubmed/25077543
http://dx.doi.org/10.1038/cddis.2014.311