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Pharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetes
Type I diabetes (T1D) is an autoimmune disease in which an immune response to pancreatic β-cells results in their loss over time. Although the conventional view is that this loss is due to autoimmune destruction, we present evidence of an additional phenomenon in which autoimmunity promotes islet en...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123101/ https://www.ncbi.nlm.nih.gov/pubmed/25077543 http://dx.doi.org/10.1038/cddis.2014.311 |