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Vitamin A dimers trigger the protracted death of retinal pigment epithelium cells
Cellular events responsible for the initiation of major neurodegenerative disorders of the eye leading to blindness, including age-related macular degeneration, Stargardt and Best diseases, are poorly understood. Accumulation of vitamin A dimers, such as N-retinylidene-N-retinylethanolamine (A2E) in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123103/ https://www.ncbi.nlm.nih.gov/pubmed/25058422 http://dx.doi.org/10.1038/cddis.2014.314 |