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Differential effects of P2Y(1) deletion on glial activation and survival of photoreceptors and amacrine cells in the ischemic mouse retina

Gliosis of retinal Müller glial cells may have both beneficial and detrimental effects on neurons. To investigate the role of purinergic signaling in ischemia-induced reactive gliosis, transient retinal ischemia was evoked by elevation of the intraocular pressure in wild-type (Wt) mice and in mice d...

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Detalles Bibliográficos
Autores principales: Pannicke, T, Frommherz, I, Biedermann, B, Wagner, L, Sauer, K, Ulbricht, E, Härtig, W, Krügel, U, Ueberham, U, Arendt, T, Illes, P, Bringmann, A, Reichenbach, A, Grosche, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123106/
https://www.ncbi.nlm.nih.gov/pubmed/25077539
http://dx.doi.org/10.1038/cddis.2014.317