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Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1

Influenza A viruses cause the respiratory illness influenza, which can be mild to fatal depending on the strain and host immune response. The flu polymerase acidic (PA), polymerase basic 1 (PB1), and polymerase basic 2 (PB2) proteins comprise the RNA-dependent RNA polymerase complex responsible for...

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Detalles Bibliográficos
Autores principales: Moen, Spencer O., Abendroth, Jan, Fairman, James W., Baydo, Ruth O., Bullen, Jameson, Kirkwood, Jennifer L., Barnes, Steve R., Raymond, Amy C., Begley, Darren W., Henkel, Greg, McCormack, Ken, Tam, Vincent C., Phan, Isabelle, Staker, Bart L., Stacy, Robin, Myler, Peter J., Lorimer, Don, Edwards, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123200/
https://www.ncbi.nlm.nih.gov/pubmed/25089892
http://dx.doi.org/10.1038/srep05944