Cargando…

Molecular Mechanisms for Biliary Phospholipid and Drug Efflux Mediated by ABCB4 and Bile Salts

On the canalicular membranes of hepatocytes, several ABC transporters are responsible for the secretion of bile lipids. Among them, ABCB4, also called MDR3, is essential for the secretion of phospholipids from hepatocytes into bile. The biliary phospholipids are associated with bile salts and choles...

Descripción completa

Detalles Bibliográficos
Autores principales: Morita, Shin-ya, Terada, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123595/
https://www.ncbi.nlm.nih.gov/pubmed/25133187
http://dx.doi.org/10.1155/2014/954781