Longitudinal Analysis Is More Powerful than Cross-Sectional Analysis in Detecting Genetic Association with Neuroimaging Phenotypes

Most existing genome-wide association analyses are cross-sectional, utilizing only phenotypic data at a single time point, e.g. baseline. On the other hand, longitudinal studies, such as Alzheimer's Disease Neuroimaging Initiative (ADNI), collect phenotypic information at multiple time points....

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Detalles Bibliográficos
Autores principales: Xu, Zhiyuan, Shen, Xiaotong, Pan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123854/
https://www.ncbi.nlm.nih.gov/pubmed/25098835
http://dx.doi.org/10.1371/journal.pone.0102312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123854/
https://www.ncbi.nlm.nih.gov/pubmed/25098835
http://dx.doi.org/10.1371/journal.pone.0102312

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