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A pilot study of leukocyte expression patterns for drug metabolizing enzyme and transporter transcripts in autoimmune glomerulonephritis

Objective: Leukocyte mRNA expression patterns of drug metabolizing enzyme genes and transporter genes that are relevant for the disposition of cyclophosphamide and mycophenolate were studied. The relationships between expression and patient-level data and pharmacokinetics were evaluated. Methods: Th...

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Detalles Bibliográficos
Autores principales: Joy, Melanie S., Roberts, Brittney V., Wang, Jinzhao, Hu, Yichun, Hogan, Susan L., Falk, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123858/
https://www.ncbi.nlm.nih.gov/pubmed/24548980
http://dx.doi.org/10.5414/CP201972