TLR9 Ligands Induce S100A8 in Macrophages via a STAT3-Dependent Pathway which Requires IL-10 and PGE(2)

S100A8 and S100A9 are highly-expressed calcium-binding proteins in neutrophils and monocytes, and in subsets of macrophages in inflammatory lesions. Unmethylated CpG motifs found in bacterial and viral DNA are potent activators of innate immunity via Toll-like receptor 9 (TLR9). S100A8, but not S100...

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Detalles Bibliográficos
Autores principales: Hsu, Kenneth, Chung, Yuen Ming, Endoh, Yasumi, Geczy, Carolyn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123874/
https://www.ncbi.nlm.nih.gov/pubmed/25098409
http://dx.doi.org/10.1371/journal.pone.0103629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123874/
https://www.ncbi.nlm.nih.gov/pubmed/25098409
http://dx.doi.org/10.1371/journal.pone.0103629

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