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Exploring the Competition between Proliferative and Invasive Cancer Phenotypes in a Continuous Spatial Model

Tumor is characterized by extensive heterogeneity with respect to its microenvironment and its genetic composition. We extend a previously developed monoclonal continuous spatial model of tumor growth to account for polyclonal cell populations and investigate the interplay between a more proliferati...

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Detalles Bibliográficos
Autores principales: Tzamali, Eleftheria, Grekas, Georgios, Marias, Konstantinos, Sakkalis, Vangelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123877/
https://www.ncbi.nlm.nih.gov/pubmed/25099885
http://dx.doi.org/10.1371/journal.pone.0103191