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Exploring the Competition between Proliferative and Invasive Cancer Phenotypes in a Continuous Spatial Model
Tumor is characterized by extensive heterogeneity with respect to its microenvironment and its genetic composition. We extend a previously developed monoclonal continuous spatial model of tumor growth to account for polyclonal cell populations and investigate the interplay between a more proliferati...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123877/ https://www.ncbi.nlm.nih.gov/pubmed/25099885 http://dx.doi.org/10.1371/journal.pone.0103191 |