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The Conditioned Place Preference Test for Assessing Welfare Consequences and Potential Refinements in a Mouse Bladder Cancer Model

Most pre-clinical analgesic efficacy assays still involve nociceptive testing in rodents. This is despite concerns as to the relevance of these tests for evaluating the pain-preventative properties of drugs. More appropriate methods would target pain rather than nociception, but these are currently...

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Detalles Bibliográficos
Autores principales: Roughan, John V., Coulter, Claire A., Flecknell, Paul A., Thomas, Huw D., Sufka, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123882/
https://www.ncbi.nlm.nih.gov/pubmed/25100208
http://dx.doi.org/10.1371/journal.pone.0103362