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The Conditioned Place Preference Test for Assessing Welfare Consequences and Potential Refinements in a Mouse Bladder Cancer Model
Most pre-clinical analgesic efficacy assays still involve nociceptive testing in rodents. This is despite concerns as to the relevance of these tests for evaluating the pain-preventative properties of drugs. More appropriate methods would target pain rather than nociception, but these are currently...
Autores principales: | Roughan, John V., Coulter, Claire A., Flecknell, Paul A., Thomas, Huw D., Sufka, Kenneth J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123882/ https://www.ncbi.nlm.nih.gov/pubmed/25100208 http://dx.doi.org/10.1371/journal.pone.0103362 |
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