Ethanol Suppresses PGC-1α Expression by Interfering with the cAMP-CREB Pathway in Neuronal Cells

Alcohol intoxication results in neuronal apoptosis, neurodegeneration and manifest with impaired balance, loss of muscle coordination and behavioral changes. One of the early events of alcohol intoxication is mitochondrial (Mt) dysfunction and disruption of intracellular redox homeostasis. The mecha...

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Detalles Bibliográficos
Autores principales: Liu, Zilong, Liu, Yongping, Gao, Rui, Li, Haixia, Dunn, Tiffany, Wu, Ping, Smith, Robert G., Sarkar, Partha S., Fang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123904/
https://www.ncbi.nlm.nih.gov/pubmed/25099937
http://dx.doi.org/10.1371/journal.pone.0104247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123904/
https://www.ncbi.nlm.nih.gov/pubmed/25099937
http://dx.doi.org/10.1371/journal.pone.0104247

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