Cargando…
Construction and Application of a Rh–Pt DNA Metalloinsertor Conjugate
[Image: see text] We report the synthesis and characterization of a bimetallic conjugate (RhPt) in which an oxaliplatin derivative is tethered to a rhodium metalloinsertor through an aminomalonate leaving group ligand. The complex interacts with DNA through metalloinsertion at a base pair mismatch f...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123934/ https://www.ncbi.nlm.nih.gov/pubmed/25032512 http://dx.doi.org/10.1021/ic501509x |