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Construction and Application of a Rh–Pt DNA Metalloinsertor Conjugate

[Image: see text] We report the synthesis and characterization of a bimetallic conjugate (RhPt) in which an oxaliplatin derivative is tethered to a rhodium metalloinsertor through an aminomalonate leaving group ligand. The complex interacts with DNA through metalloinsertion at a base pair mismatch f...

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Detalles Bibliográficos
Autores principales:	Weidmann, Alyson G., Barton, Jacqueline K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123934/ https://www.ncbi.nlm.nih.gov/pubmed/25032512 http://dx.doi.org/10.1021/ic501509x

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