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Targeting Breast Tumors with pH (Low) Insertion Peptides

[Image: see text] Extracellular acidity is associated with tumor progression. Elevated glycolysis and acidosis promote the appearance of aggressive malignant cells with enhanced multidrug resistance. Thus, targeting of tumor acidity can open new avenues in diagnosis and treatment of aggressive tumor...

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Detalles Bibliográficos
Autores principales: Adochite, Ramona-Cosmina, Moshnikova, Anna, Carlin, Sean D., Guerrieri, Renato A., Andreev, Oleg A., Lewis, Jason S., Reshetnyak, Yana K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123937/
https://www.ncbi.nlm.nih.gov/pubmed/25004202
http://dx.doi.org/10.1021/mp5002526