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Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover

[Image: see text] Ewing sarcoma is a cancer of bone and soft tissue in children that is characterized by a chromosomal translocation involving EWS and an Ets family transcription factor, most commonly Fli-1. EWS-Fli-1 fusion accounts for 85% of cases. The growth and survival of Ewing sarcoma cells a...

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Detalles Bibliográficos
Autores principales: Elzi, David J., Song, Meihua, Hakala, Kevin, Weintraub, Susan T., Shiio, Yuzuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123944/
https://www.ncbi.nlm.nih.gov/pubmed/24999758
http://dx.doi.org/10.1021/pr500387m