Off-Line Multidimensional Liquid Chromatography and Auto Sampling Result in Sample Loss in LC/LC–MS/MS

[Image: see text] Large-scale proteomics often employs two orthogonal separation methods to fractionate complex peptide mixtures. Fractionation can involve ion exchange separation coupled to reversed-phase separation or, more recently, two reversed-phase separations performed at different pH values....

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Detalles Bibliográficos
Autores principales: Magdeldin, Sameh, Moresco, James J., Yamamoto, Tadashi, Yates, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123945/
https://www.ncbi.nlm.nih.gov/pubmed/25040086
http://dx.doi.org/10.1021/pr500530e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123945/
https://www.ncbi.nlm.nih.gov/pubmed/25040086
http://dx.doi.org/10.1021/pr500530e

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