Effects of combined netupitant and palonosetron (NEPA), a cancer supportive care antiemetic, on the ECG of healthy subjects: an ICH E14 thorough QT trial

Chemotherapy-induced nausea and vomiting is ranked among the worst side effects of chemotherapy. NEPA is an oral fixed-dose combination antiemetic under development, consisting of netupitant 300 mg, a highly selective NK(1) receptor antagonist (RA), and palonosetron 0.5 mg, a pharmacologically and c...

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Detalles Bibliográficos
Autores principales: Spinelli, Tulla, Moresino, Cecilia, Baumann, Sybille, Timmer, Wolfgang, Schultz, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124105/
https://www.ncbi.nlm.nih.gov/pubmed/25105088
http://dx.doi.org/10.1186/2193-1801-3-389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124105/
https://www.ncbi.nlm.nih.gov/pubmed/25105088
http://dx.doi.org/10.1186/2193-1801-3-389

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