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Effects of combined netupitant and palonosetron (NEPA), a cancer supportive care antiemetic, on the ECG of healthy subjects: an ICH E14 thorough QT trial

Chemotherapy-induced nausea and vomiting is ranked among the worst side effects of chemotherapy. NEPA is an oral fixed-dose combination antiemetic under development, consisting of netupitant 300 mg, a highly selective NK(1) receptor antagonist (RA), and palonosetron 0.5 mg, a pharmacologically and c...

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Detalles Bibliográficos
Autores principales:	Spinelli, Tulla, Moresino, Cecilia, Baumann, Sybille, Timmer, Wolfgang, Schultz, Armin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124105/ https://www.ncbi.nlm.nih.gov/pubmed/25105088 http://dx.doi.org/10.1186/2193-1801-3-389

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