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The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression

BACKGROUND: Insulin producing beta cell and glucagon producing alpha cells are colocalized in pancreatic islets in an arrangement that facilitates the coordinated release of the two principal hormones that regulate glucose homeostasis and prevent both hypoglycemia and diabetes. However, this intrica...

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Detalles Bibliográficos
Autores principales: Benner, Christopher, van der Meulen, Talitha, Cacéres, Elena, Tigyi, Kristof, Donaldson, Cynthia J, Huising, Mark O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124169/
https://www.ncbi.nlm.nih.gov/pubmed/25051960
http://dx.doi.org/10.1186/1471-2164-15-620