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The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression
BACKGROUND: Insulin producing beta cell and glucagon producing alpha cells are colocalized in pancreatic islets in an arrangement that facilitates the coordinated release of the two principal hormones that regulate glucose homeostasis and prevent both hypoglycemia and diabetes. However, this intrica...
Autores principales: | Benner, Christopher, van der Meulen, Talitha, Cacéres, Elena, Tigyi, Kristof, Donaldson, Cynthia J, Huising, Mark O |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124169/ https://www.ncbi.nlm.nih.gov/pubmed/25051960 http://dx.doi.org/10.1186/1471-2164-15-620 |
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