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The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration

During brain development, radial glial cells possess an apico-basal polarity and are coupled by adherens junctions (AJs) to an F-actin belt. To elucidate the role of the actin, we conditionally deleted the key component α-E-catenin in the developing cerebral cortex. Deletion at early stages resulted...

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Detalles Bibliográficos
Autores principales: Schmid, Marie-Theres, Weinandy, Franziska, Wilsch-Bräuninger, Michaela, Huttner, Wieland B., Cappello, Silvia, Götz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124588/
https://www.ncbi.nlm.nih.gov/pubmed/25147501
http://dx.doi.org/10.3389/fncel.2014.00215