Cargando…
A simple structure-based model for the prediction of HIV-1 co-receptor tropism
BACKGROUND: Human Immunodeficiency Virus 1 enters host cells through interaction of its V3 loop (which is part of the gp120 protein) with the host cell receptor CD4 and one of two co-receptors, namely CCR5 or CXCR4. Entry inhibitors binding the CCR5 co-receptor can prevent viral entry. As these drug...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124776/ https://www.ncbi.nlm.nih.gov/pubmed/25120583 http://dx.doi.org/10.1186/1756-0381-7-14 |