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Alternative Splicing Generates Different Parkin Protein Isoforms: Evidences in Human, Rat, and Mouse Brain

Parkinson protein 2, E3 ubiquitin protein ligase (PARK2) gene mutations are the most frequent causes of autosomal recessive early onset Parkinson's disease and juvenile Parkinson disease. Parkin deficiency has also been linked to other human pathologies, for example, sporadic Parkinson disease,...

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Detalles Bibliográficos
Autores principales: Scuderi, Soraya, La Cognata, Valentina, Drago, Filippo, Cavallaro, Sebastiano, D'Agata, Velia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124806/
https://www.ncbi.nlm.nih.gov/pubmed/25136611
http://dx.doi.org/10.1155/2014/690796