KDM6 Demethylase Independent Loss of Histone H3 Lysine 27 Trimethylation during Early Embryonic Development

The early mammalian embryo utilizes histone H3 lysine 27 trimethylation (H3K27me3) to maintain essential developmental genes in a repressive chromatin state. As differentiation progresses, H3K27me3 is removed in a distinct fashion to activate lineage specific patterns of developmental gene expressio...

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Detalles Bibliográficos
Autores principales: Shpargel, Karl B., Starmer, Joshua, Yee, Della, Pohlers, Michael, Magnuson, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125042/
https://www.ncbi.nlm.nih.gov/pubmed/25101834
http://dx.doi.org/10.1371/journal.pgen.1004507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125042/
https://www.ncbi.nlm.nih.gov/pubmed/25101834
http://dx.doi.org/10.1371/journal.pgen.1004507

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