Cargando…

KDM6 Demethylase Independent Loss of Histone H3 Lysine 27 Trimethylation during Early Embryonic Development

The early mammalian embryo utilizes histone H3 lysine 27 trimethylation (H3K27me3) to maintain essential developmental genes in a repressive chromatin state. As differentiation progresses, H3K27me3 is removed in a distinct fashion to activate lineage specific patterns of developmental gene expressio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shpargel, Karl B., Starmer, Joshua, Yee, Della, Pohlers, Michael, Magnuson, Terry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125042/ https://www.ncbi.nlm.nih.gov/pubmed/25101834 http://dx.doi.org/10.1371/journal.pgen.1004507

Ejemplares similares

UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development
por: Shpargel, Karl B., et al.
Publicado: (2012)

Histone lysine demethylases in mammalian embryonic development
por: Shen, Hongjie, et al.
Publicado: (2017)

Histone 3 Lysine 27 Trimethylation Signature in Breast Cancer
por: Borkiewicz, Lidia
Publicado: (2021)

Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos
por: Glanzner, Werner Giehl, et al.
Publicado: (2020)

Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
por: Leurs, Ulrike, et al.
Publicado: (2014)

Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling
por: Tsurumi, Amy, et al.
Publicado: (2013)

Identification of the KDM2/7 Histone Lysine Demethylase Subfamily Inhibitor and its Antiproliferative Activity
por: Suzuki, Takayoshi, et al.
Publicado: (2013)

Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
por: Zhang, Qing-Jun, et al.
Publicado: (2018)

EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation
por: Mu, Weipeng, et al.
Publicado: (2018)

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells
por: Wu, Liangtang, et al.
Publicado: (2015)

CORRIGENDUM: Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signalling
por: Tsurumi, Amy, et al.
Publicado: (2014)

Discovery of a Highly Selective Cell‐Active Inhibitor of the Histone Lysine Demethylases KDM2/7
por: Gerken, Philip A., et al.
Publicado: (2017)

The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations
por: Hancock, Rebecca L, et al.
Publicado: (2017)

Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM)
por: Lapidot, Moshe, et al.
Publicado: (2021)

Whole-Genome Analysis of Histone H3 Lysine 27 Trimethylation in Arabidopsis
por: Zhang, Xiaoyu, et al.
Publicado: (2007)

The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis
por: Backe, Marie Balslev, et al.
Publicado: (2019)

Histone H3.3 maintains genome integrity during mammalian development
por: Jang, Chuan-Wei, et al.
Publicado: (2015)

Contrasting roles for histone 3 lysine 27 demethylases in acute lymphoblastic leukemia
por: Ntziachristos, Panagiotis, et al.
Publicado: (2014)

Benzo[b]tellurophenes as a Potential Histone H3 Lysine 9 Demethylase (KDM4) Inhibitor
por: Kim, Yoon-Jung, et al.
Publicado: (2019)

Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation
por: Duan, Lingling, et al.
Publicado: (2019)

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer
por: Blair, Lauren P., et al.
Publicado: (2011)

KDM5 lysine demethylases are involved in maintenance of 3′UTR length
por: Blair, Lauren P., et al.
Publicado: (2016)

Histone H3 Lysine 4 and 27 Trimethylation Landscape of Human Alzheimer’s Disease
por: Persico, Giuseppe, et al.
Publicado: (2022)

Histone lysine demethylases in Drosophila melanogaster
por: Holowatyj, Andreana, et al.
Publicado: (2015)

Histone demethylase lysine demethylase 5B in development and cancer
por: Han, Mengjiao, et al.
Publicado: (2016)

Echinococcus granulosus cyst fluid inhibits KDM6B-mediated demethylation of trimethylated histone H3 lysine 27 and interleukin-1β production in macrophages
por: Lin, Ruolin, et al.
Publicado: (2023)

Genome-Wide Profiling of Histone H3 Lysine 4 and Lysine 27 Trimethylation Reveals an Epigenetic Signature in Prostate Carcinogenesis
por: Ke, Xi-Song, et al.
Publicado: (2009)

Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C
por: Grafodatskaya, Daria, et al.
Publicado: (2013)

Oocyte-Specific Knockout of Histone Lysine Demethylase KDM2a Compromises Fertility by Blocking the Development of Follicles and Oocytes
por: Xiong, Xianrong, et al.
Publicado: (2022)

Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature
por: Abu-Hanna, Jeries, et al.
Publicado: (2022)

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila
por: Drelon, Coralie, et al.
Publicado: (2018)

The nuclear bodies formed by histone demethylase KDM7A
por: Ming, Hui, et al.
Publicado: (2020)

Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53
por: Ramadoss, Sivakumar, et al.
Publicado: (2016)

Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC
por: Wei, Yongyue, et al.
Publicado: (2018)

KDM2A/B lysine demethylases and their alternative isoforms in development and disease
por: Vacík, Tomáš, et al.
Publicado: (2018)

The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons
por: Wang, Yifan, et al.
Publicado: (2023)

Targeting glioma stem‐like cell survival and chemoresistance through inhibition of lysine‐specific histone demethylase KDM2B
por: Staberg, Mikkel, et al.
Publicado: (2018)

MicroRNA let-7i Inhibits Histone Lysine Demethylase KDM5B to Halt Esophageal Cancer Progression
por: Yang, Yang, et al.
Publicado: (2020)

The Histone H3 Lysine 27-Specific Demethylase Jmjd3 Is Required for Neural Commitment
por: Burgold, Thomas, et al.
Publicado: (2008)

Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation
por: Manna, Sugata, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_lt9te7q3kran4f7l41edv5uac4