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A Micellar On-Pathway Intermediate Step Explains the Kinetics of Prion Amyloid Formation

In a previous work by Alvarez-Martinez et al. (2011), the authors pointed out some fallacies in the mainstream interpretation of the prion amyloid formation. It appeared necessary to propose an original hypothesis able to reconcile the in vitro data with the predictions of a mathematical model descr...

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Detalles Bibliográficos
Autores principales: Hingant, Erwan, Fontes, Pascaline, Alvarez-Martinez, Maria Teresa, Arnaud, Jacques-Damien, Liautard, Jean-Pierre, Pujo-Menjouet, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125056/
https://www.ncbi.nlm.nih.gov/pubmed/25101755
http://dx.doi.org/10.1371/journal.pcbi.1003735