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Tethering Sister Centromeres to Each Other Suggests the Spindle Checkpoint Detects Stretch within the Kinetochore

The spindle checkpoint ensures that newly born cells receive one copy of each chromosome by preventing chromosomes from segregating until they are all correctly attached to the spindle. The checkpoint monitors tension to distinguish between correctly aligned chromosomes and those with both sisters a...

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Detalles Bibliográficos
Autores principales: Nannas, Natalie J., Murray, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125069/
https://www.ncbi.nlm.nih.gov/pubmed/25101645
http://dx.doi.org/10.1371/journal.pgen.1004492