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Branch Migration Prevents DNA Loss during Double-Strand Break Repair

The repair of DNA double-strand breaks must be accurate to avoid genomic rearrangements that can lead to cell death and disease. This can be accomplished by promoting homologous recombination between correctly aligned sister chromosomes. Here, using a unique system for generating a site-specific DNA...

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Detalles Bibliográficos
Autores principales: Mawer, Julia S. P., Leach, David R. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125073/
https://www.ncbi.nlm.nih.gov/pubmed/25102287
http://dx.doi.org/10.1371/journal.pgen.1004485