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A System for Genome-Wide Histone Variant Dynamics In ES Cells Reveals Dynamic MacroH2A2 Replacement at Promoters

Dynamic exchange of a subset of nucleosomes in vivo plays important roles in epigenetic inheritance of chromatin states, chromatin insulator function, chromosome folding, and the maintenance of the pluripotent state of embryonic stem cells. Here, we extend a pulse-chase strategy for carrying out gen...

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Detalles Bibliográficos
Autores principales: Yildirim, Ozlem, Hung, Jui-Hung, Cedeno, Ryan J., Weng, Zhiping, Lengner, Christopher J., Rando, Oliver J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125097/
https://www.ncbi.nlm.nih.gov/pubmed/25102063
http://dx.doi.org/10.1371/journal.pgen.1004515