Cargando…

A Novel Dual Allosteric Activation Mechanism of Escherichia coli ADP-Glucose Pyrophosphorylase: The Role of Pyruvate

Fructose-1,6-bisphosphate activates ADP-glucose pyrophosphorylase and the synthesis of glycogen in Escherichia coli. Here, we show that although pyruvate is a weak activator by itself, it synergically enhances the fructose-1,6-bisphosphate activation. They increase the enzyme affinity for each other...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asención Diez, Matías D., Aleanzi, Mabel C., Iglesias, Alberto A., Ballicora, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125136/ https://www.ncbi.nlm.nih.gov/pubmed/25102309 http://dx.doi.org/10.1371/journal.pone.0103888

Ejemplares similares

A Chimeric UDP-Glucose Pyrophosphorylase Produced by Protein Engineering Exhibits Sensitivity to Allosteric Regulators
por: Asención Diez, Matías D., et al.
Publicado: (2013)

Allosteric Control of Substrate Specificity of the Escherichia coli ADP-Glucose Pyrophosphorylase
por: Ebrecht, Ana C., et al.
Publicado: (2017)

On the Roles of Wheat Endosperm ADP-Glucose Pyrophosphorylase Subunits
por: Ferrero, Danisa M. L., et al.
Publicado: (2018)

Phosphorylation of ADP-Glucose Pyrophosphorylase During Wheat Seeds Development
por: Ferrero, Danisa M. L., et al.
Publicado: (2020)

Mapping of a Regulatory Site of the Escherichia coli ADP-Glucose Pyrophosphorylase
por: Bhayani, Jaina A., et al.
Publicado: (2019)

Carbohydrate Metabolism in Bacteria: Alternative Specificities in ADP-Glucose Pyrophosphorylases Open Novel Metabolic Scenarios and Biotechnological Tools
por: Bhayani, Jaina, et al.
Publicado: (2022)

On the Kinetic and Allosteric Regulatory Properties of the ADP-Glucose Pyrophosphorylase from Rhodococcus jostii: An Approach to Evaluate Glycogen Metabolism in Oleaginous Bacteria
por: Cereijo, Antonela E., et al.
Publicado: (2016)

Site‐directed mutagenesis of Serine‐72 reveals the location of the fructose 6‐phosphate regulatory site of the Agrobacterium tumefaciens ADP‐glucose pyrophosphorylase
por: Alghamdi, Mashael A., et al.
Publicado: (2022)

A critical inter‐subunit interaction for the transmission of the allosteric signal in the Agrobacterium tumefaciens ADP‐glucose pyrophosphorylase
por: Patel, Hiral P., et al.
Publicado: (2023)

The ancestral activation promiscuity of ADP-glucose pyrophosphorylases from oxygenic photosynthetic organisms
por: Kuhn, Misty L, et al.
Publicado: (2013)

Unraveling the Activation Mechanism of the Potato Tuber ADP-Glucose Pyrophosphorylase
por: Figueroa, Carlos M., et al.
Publicado: (2013)

Resurrecting the Regulatory Properties of the Ostreococcus tauri ADP-Glucose Pyrophosphorylase Large Subunit
por: Figueroa, Carlos M., et al.
Publicado: (2018)

On the Ancestral UDP-Glucose Pyrophosphorylase Activity of GalF from Escherichia coli
por: Ebrecht, Ana C., et al.
Publicado: (2015)

Comparative computational analysis of ADP Glucose Pyrophosphorylase in plants
por: Rani, Saroj, et al.
Publicado: (2013)

Duplications and functional divergence of ADP-glucose pyrophosphorylase genes in plants
por: Georgelis, Nikolaos, et al.
Publicado: (2008)

On the stability of nucleoside diphosphate glucose metabolites: implications for studies of plant carbohydrate metabolism
por: Hill, Benjamin L, et al.
Publicado: (2017)

Investigation of the Interaction between the Large and Small Subunits of Potato ADP-Glucose Pyrophosphorylase
por: Barıs, Ibrahim, et al.
Publicado: (2009)

Mechanism Underlying Heat Stability of the Rice Endosperm Cytosolic ADP-Glucose Pyrophosphorylase
por: Hwang, Seon-Kap, et al.
Publicado: (2019)

Characterization of Various Subunit Combinations of ADP-Glucose Pyrophosphorylase in Duckweed (Landoltia punctata)
por: Wang, Mingxiu, et al.
Publicado: (2022)

Monofluorophosphate Blocks Internal Polysaccharide Synthesis in Streptococcus mutans
por: Demonte, Ana M., et al.
Publicado: (2017)

Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium tuberculosis
por: Asención Diez, Matías D., et al.
Publicado: (2015)

Cloning and characterization of Escherichia coli DUF299: a bifunctional ADP-dependent kinase - P(i)-dependent pyrophosphorylase from bacteria
por: Burnell, Jim N
Publicado: (2010)

Seed-specific suppression of ADP-glucose pyrophosphorylase in Camelina sativa increases seed size and weight
por: Na, GunNam, et al.
Publicado: (2018)

Activity and expression of ADP-glucose pyrophosphorylase during rhizome formation in lotus (Nelumbo nucifera Gaertn.)
por: Cheng, Libao, et al.
Publicado: (2016)

ADP‐glucose pyrophosphorylase genes, associated with kernel weight, underwent selection during wheat domestication and breeding
por: Hou, Jian, et al.
Publicado: (2017)

Analysis of ADP-glucose pyrophosphorylase expression during turion formation induced by abscisic acid in Spirodela polyrhiza (greater duckweed)
por: Wang, Wenqin, et al.
Publicado: (2012)

Carbon Dynamics, Development and Stress Responses in Arabidopsis: Involvement of the APL4 Subunit of ADP-Glucose Pyrophosphorylase (Starch Synthesis)
por: Sulmon, Cécile, et al.
Publicado: (2011)

Insights of interaction between small and large subunits of ADP-glucose pyrophosphorylase from bread wheat (Triticum aestivum L.)
por: Danishuddin, Mohd, et al.
Publicado: (2011)

Plastidic phosphoglucomutase and ADP-glucose pyrophosphorylase mutants impair starch synthesis in rice pollen grains and cause male sterility
por: Lee, Sang-Kyu, et al.
Publicado: (2016)

The Maize Corngrass1 miRNA-Regulated Developmental Alterations Are Restored by a Bacterial ADP-Glucose Pyrophosphorylase in Transgenic Tobacco
por: Ligaba-Osena, Ayalew, et al.
Publicado: (2018)

Exploring Redox Modulation of Plant UDP-Glucose Pyrophosphorylase
por: Decker, Daniel, et al.
Publicado: (2023)

A Novel Allosteric Inhibitor of the Uridine Diphosphate N-Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei
por: Urbaniak, Michael D., et al.
Publicado: (2013)

Novel Bioengineered Cassava Expressing an Archaeal Starch Degradation System and a Bacterial ADP-Glucose Pyrophosphorylase for Starch Self-Digestibility and Yield Increase
por: Ligaba-Osena, Ayalew, et al.
Publicado: (2018)

MePHD1 as a PHD-Finger Protein Negatively Regulates ADP-Glucose Pyrophosphorylase Small Subunit1a Gene in Cassava
por: Ma, Ping’an, et al.
Publicado: (2018)

Enhancement of Heat Stability and Kinetic Parameters of the Maize Endosperm ADP-Glucose Pyrophosphorylase by Mutagenesis of Amino Acids in the Small Subunit With High B Factors
por: Boehlein, Susan K., et al.
Publicado: (2018)

From the archives: Circadian clock regulation of phyA, regulation of Z-ring positioning in chloroplast division, and ADP–glucose pyrophosphorylase subunit interactions
por: Yadav, Arpita
Publicado: (2023)

Pyruvate production using engineered Escherichia coli
por: Akita, Hironaga, et al.
Publicado: (2016)

The Production and Utilization of GDP-glucose in the Biosynthesis of Trehalose 6-Phosphate by Streptomyces venezuelae
por: Asención Diez, Matías D., et al.
Publicado: (2017)

Effects of Magnesium, Pyrophosphate and Phosphonates on Pyrophosphorolytic Reaction of UDP-Glucose Pyrophosphorylase
por: Kleczkowski, Leszek A., et al.
Publicado: (2022)

Characterization of Pyruvate Uptake in Escherichia coli K-12
por: Kreth, Jens, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_td0s6lcm0eo5cfni6c7ibn2bb1