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Structural and Functional Analysis of a Platelet-Activating Lysophosphatidylcholine of Trypanosoma cruzi

BACKGROUND: Trypanosoma cruzi is the causative agent of the life-threatening Chagas disease, in which increased platelet aggregation related to myocarditis is observed. Platelet-activating factor (PAF) is a potent intercellular lipid mediator and second messenger that exerts its activity through a P...

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Detalles Bibliográficos
Autores principales: Gazos-Lopes, Felipe, Oliveira, Mauricio M., Hoelz, Lucas V. B., Vieira, Danielle P., Marques, Alexandre F., Nakayasu, Ernesto S., Gomes, Marta T., Salloum, Nasim G., Pascutti, Pedro G., Souto-Padrón, Thaïs, Monteiro, Robson Q., Lopes, Angela H., Almeida, Igor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125143/
https://www.ncbi.nlm.nih.gov/pubmed/25101628
http://dx.doi.org/10.1371/journal.pntd.0003077