A Structural Insight into Major Groove Directed Binding of Nitrosourea Derivative Nimustine with DNA: A Spectroscopic Study

Nitrosourea therapeutics occupies a definite place in cancer therapy but its exact mechanism of action has yet to be established. Nimustine, a chloroethyl nitrosourea derivative, is used to treat various types of malignancy including gliomas. The present work focuses on the understanding of nimustin...

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Detalles Bibliográficos
Autores principales: Agarwal, Shweta, Jangir, Deepak Kumar, Mehrotra, Ranjana, Lohani, Neelam, Rajeswari, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125164/
https://www.ncbi.nlm.nih.gov/pubmed/25101667
http://dx.doi.org/10.1371/journal.pone.0104115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125164/
https://www.ncbi.nlm.nih.gov/pubmed/25101667
http://dx.doi.org/10.1371/journal.pone.0104115

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