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Inhibition of Histone H3K9 Acetylation by Anacardic Acid Can Correct the Over-Expression of Gata4 in the Hearts of Fetal Mice Exposed to Alcohol during Pregnancy

BACKGROUND: Cardiovascular malformations can be caused by abnormalities in Gata4 expression during fetal development. In a previous study, we demonstrated that ethanol exposure could lead to histone hyperacetylation and Gata4 over-expression in fetal mouse hearts. However, the potential mechanisms o...

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Detalles Bibliográficos
Autores principales: Peng, Chang, Zhu, Jing, Sun, Hui-Chao, Huang, Xu-Pei, Zhao, Wei-An, Zheng, Min, Liu, Ling-Juan, Tian, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125174/
https://www.ncbi.nlm.nih.gov/pubmed/25101666
http://dx.doi.org/10.1371/journal.pone.0104135