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Terpenes Increase the Lipid Dynamics in the Leishmania Plasma Membrane at Concentrations Similar to Their IC(50) Values

Although many terpenes have shown antitumor, antibacterial, antifungal, and antiparasitic activity, the mechanism of action is not well established. Electron paramagnetic resonance (EPR) spectroscopy of the spin-labeled 5-doxyl stearic acid revealed remarkable fluidity increases in the plasma membra...

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Detalles Bibliográficos
Autores principales: Camargos, Heverton Silva, Moreira, Rodrigo Alves, Mendanha, Sebastião Antonio, Fernandes, Kelly Souza, Dorta, Miriam Leandro, Alonso, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125203/
https://www.ncbi.nlm.nih.gov/pubmed/25101672
http://dx.doi.org/10.1371/journal.pone.0104429